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Anti-Elafin/ESI Rabbit pAb (100 μl)
| Reactivity: | H |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Elafin/ESI rabbit polyclonal antibody |
Gene Name: | Elafin |
Synonyms: | cementoin, Elafin, Elastase specific inhibitor, ESI, Peptidase inhibitor 3, PI-3, PI3, Protease inhibitor WAP3, SKALP, WAP3, WFDC14, Skin-derived antileukoproteinase, WAP four-disulfide core domain protein 14 |
Immunogen: | Recombinant protein corresponding to Mouse Elafin/ESI |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Uniprot ID: | P19957 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human | 1: 1000-1: 2000 | esophageal cancer, tonsil, esophagus, skin |
Background
This gene encodes an elastase-specific inhibitor that functions as an antimicrobial peptide against Gram-positive and Gram-negative bacteria, and fungal pathogens. The protein contains a WAP-type four-disulfide core (WFDC) domain, and is thus a member of the WFDC domain family. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the centromeric cluster. Expression of this gene is upgulated by bacterial lipopolysaccharides and cytokines.
Images
 | Immunohistochemistry analysis of paraffin-embedded human esophageal cancer using Elafin (GB113877) at dilution of 1: 2000 |
 | Immunohistochemistry analysis of paraffin-embedded human esophageal cancer using Elafin (GB113877) at dilution of 1: 2000 |
 | Immunohistochemistry analysis of paraffin-embedded human tonsil using Elafin (GB113877) at dilution of 1: 2000 |
 | Immunofluorescent analysis of paraformaldehyde-fixed human esophagus using Elafin (GB113877) at dilution of 1: 2000 |
 | Immunofluorescent analysis of paraformaldehyde-fixed human skin using Elafin (GB113877) at dilution of 1: 2000 |
 | Immunofluorescent analysis of paraformaldehyde-fixed human tonsil using Elafin (GB113877) at dilution of 1: 2000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
