Your shopping cart is empty!
Anti-Endothelin 1 Rabbit pAb (100 μl)
| Reactivity: | H |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Endothelin 1 rabbit polyclonal antibody |
Gene Name: | Endothelin-1 |
Synonyms: | EDN1, ARCND3, ET1, ET-1, HDLCQ7, PPET1, QME, Endothelin 1 |
Immunogen: | Recombinant protein corresponding to Mouse Endothelin 1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 24 kDa |
Observed MW. | 24 kDa |
Uniprot ID: | P22387 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse | 1: 500-1: 1000 | liver, lung, kiney |
Background
Endothelin 1 (ET-1), also known as preproendothelin-1 (PPET1), is a potent vasoconstrictor that in humans is encoded by the EDN1 gene and produced by vascular endothelial cells. The protein encoded by this gene is proteolytically processed to release a secreted peptide termed endothelin 1. Endothelin 1 is one of three isoforms of human endothelin.
Preproendothelin is precursor of the peptide ET-1. Endothelial cells convert preproendothelin to proendothelin and subsequently to mature endothelin, which the cells release.
Images
 |
Western blot analysis of Endothelin1 (GB11557) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
