Reactivity: | R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | Endothelin-1 |
Synonyms: | EDN1, endothelin 1, ET 1 Big endothelin 1, ET1, HDLCQ7, PPET1, Preproendothelin 1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Endothelin1 |
Uniprot ID: | P22387 |
Isotype: | lgG |
Purity: | Affinity purification |
Subcellular location: | Secreted |
Predicted MW. / Observed MW. | 22 kDa / 24 kDa |
Product Usage Information
WB | Rat | 1: 300-1: 500 | lung |
Background
Endothelins are endothelium-derived vasoconstrictor peptides. Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells.
Images
Western blot analysis of Endothelin 1 (GB115574) at dilution of 1: 300 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |