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| Reactivity: | M,R & M,R |
| Applications: | IHC & IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Epithelial cell adhesion molecule |
Synonyms: | EPCAM, DIAR5, EGP-2, EGP314, EGP40, ESA, HNPCC8, KS1/4, KSA, M4S1, MIC18, MK-1, TACSTD1, TROP1, epithelial cell adhesion molecule |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse EPCAM |
Uniprot ID: | Q99JW5 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Lateral cell membrane, Cell junction |
Predicted MW. / Observed MW. | 35 kDa / 35-40 kDa |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | lung |
IHC/IF | Mouse, Rat | 1: 200-1: 2000 | colon, kidney, small intestine, stomach |
Background
May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E.
Images
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Western blot analysis of Epcam (GB11274) at dilution of 1: 500 |
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Immunohistochemistry of paraffin embedded mouse colon using EPCAM (GB11274) at dilution of 1: 1000 (400x lens) |
| Immunohistochemistry of paraffin embedded rat colon using EPCAM (GB11274) at dilution of 1: 1000 (400x lens) |
| Immunofluorescence of paraffin embedded mouse colon using EPCAM (GB11274) at dilution of 1: 500 (400x lens) |
| Immunofluorescence of paraffin embedded mouse kidney using EPCAM (GB11274) at dilution of 1: 500 (400x lens) |
| Immunofluorescence of paraffin embedded rat small intestine using EPCAM (GB11274) at dilution of 1: 500 (400x lens) |
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Immunofluorescence of paraffin embedded rat stomach using EPCAM (GB11274) at dilution of 1: 500 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
