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Anti-Ephrin B1 Rabbit pAb (100 μl)
| Reactivity: | H |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Ephrin B1 rabbit polyclonal antibody |
Gene Name: | Ephrin-B1 |
Synonyms: | EFL-3, ELK-L, EPH-related receptor tyrosine kinase ligand 2, LERK-2, EFNB1, EFL3, EPLG2, LERK2 |
Immunogen: | Recombinant protein corresponding to Mouse Ephrin B1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 38 kDa |
Observed MW. | 45 kDa |
Uniprot ID: | P98172 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human | 1: 500-1: 1000 | PC-3, Hacat, HepG2 |
Background
Ephrin-B1, also known as LERK-2, ELK-L, EFL-3, Cek5-L, and STRA-1 , is a member of the ephrin ligand family which binds members of the Eph receptor family. Several signaling molecules have been shown to interact with the cytoplasmic region, although specific signaling roles have yet to be elucidated. Ephrin-B1 has been shown to bind EphA3, EphB1, EphB2, EphB3, and EphB4. The extracellular domains of human and mouse Ephrin-B1 share 94% amino acid identity. Only membrane-bound or Fc-clustered ligands are capable of activating the receptor in vitro. Soluble monomeric ligands bind the receptor but do not induce receptor autophosphorylation and activation. In vivo, the ligands and receptors display reciprocal expression. It has been found that nearly all receptors and ligands are expressed in developing and adult neural tissue. The Eph/ephrin families also appear to play a role in angiogenesis.
Images
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Western blot analysis of EphrinB1 (GB111417) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
