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Anti-Exonuclease 1 Rabbit pAb (100 μl)
| Reactivity: | R & R |
| Applications: | IHC & IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Exonuclease 1 rabbit polyclonal |
Gene Name: | Exonuclease 1 |
Synonyms: | mExo1, Exonuclease 1, Exo1, HEX1, hExoI, rad2 nuclease family member, Homolog of S, cerevisiae exonuclease 1 |
Immunogen: | Recombinant protein corresponding to Mouse Exonuclease 1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Rat | 1: 900-1: 1800 | testis, brain |
IF | Rat | 1: 900-1: 1800 | brain |
Background
EXO1 also named as HEX1, is a protein with 5' to 3' exonuclease activity as well as an RNase H activity, which belongs to the XPG/RAD2 endonuclease family.EXO1 as 5'->3' double-stranded DNA exonuclease, which may also possess a cryptic 3'->5' double-stranded DNA exonuclease activity. EXO1 functions in DNA mismatch repair (MMR) to excise mismatch-containing DNA tracts directed by strand breaks located either 5' or 3' to the mismatch.
Images
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Immunohistochemistry analysis of paraffin-embedded rat testis using Exo1 (GB111399) at dilution of 1: 900 |
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Immunohistochemistry analysis of paraffin-embedded rat brain using Exo1 (GB111399) at dilution of 1: 900 |
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Immunofluorescent analysis of paraformaldehyde-fixed rat brain using Exo1 (GB111399) at dilution of 1: 900 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
