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Anti-FABP-1 Rabbit pAb (100 μl)
| Reactivity: | M,R & M,R |
| Applications: | WB & IHC |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | FABP-1 rabbit polyclonal |
Gene Name: | Aspartate aminotransferase, mitochondrial |
Synonyms: | FABP 1, FABPpm, Fatty acid binding protein, GOT2, KAT4, KATIV, mAspAT, mitAAT, Transaminase A |
Immunogen: | Recombinant protein corresponding to Mouse FABP-1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane, Secret |
Predicted MW. | 47 kDa |
Observed MW. | 43 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 1000-1: 2000 | brain, liver, kidney, heart |
IHC | Mouse, Rat | 1: 900-1: 1800 | liver cancer, kidney, lung, colon, spinal cord |
Background
GOT2 [Glutamate oxaloacetate transaminase] is a ubiquitous pyridoxal phosphate dependent enzyme which exists in both mitochondrial and cytosolic forms. The enzyme plays an important role in amino acid metabolism and in the urea and tricarboxylic acid cycles. The 2 isoenzymes are homodimeric. In liver about 80% of the enzyme activity is mitochondrial in origin, whereas in serum the enzyme activity is largely cytosolic. Although the mitochondrial and soluble forms of GOT are coded by different chromosomes, the 2 show close homology in amino acid sequence and were presumably derived from a common ancestral gene.
Images
| Western blot analysis of FABP-1 (GB113130) at dilution of 1: 2000 |
| Western blot analysis of FABP-1 (GB113130) at dilution of 1: 2000 |
| Immunohistochemistry analysis of paraffin-embedded human liver cancer using FABP-1 (GB113130) at dilution of 1: 1800 |
| Immunohistochemistry analysis of paraffin-embedded human kidney using FABP-1 (GB113130) at dilution of 1: 1800 |
| Immunohistochemistry analysis of paraffin-embedded rat kidney using FABP-1 (GB113130) at dilution of 1: 1800 |
| Immunohistochemistry analysis of paraffin-embedded mouse lung using FABP-1 (GB113130) at dilution of 1: 1800 |
| Immunohistochemistry analysis of paraffin-embedded rat lung using FABP-1 (GB113130) at dilution of 1: 1800 |
| Immunohistochemistry analysis of paraffin-embedded rat colon using FABP-1 (GB113130) at dilution of 1: 1800 |
| Immunohistochemistry analysis of paraffin-embedded rat skin using FABP-1 (GB113130) at dilution of 1: 1800 |
| Immunohistochemistry analysis of paraffin-embedded rat spinal cord using FABP-1 (GB113130) at dilution of 1: 1800 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
