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Anti-FAM20C Rabbit pAb (100 μl)
| Reactivity: | R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Extracellular serine/threonine protein kinase FAM20C |
Synonyms: | Dentin matrix protein 4, DMP 4, DMP4, FAM20C, Protein FAM20C, RNS |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse FAM20C |
Uniprot ID: | Q5MJS3 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 66 kDa / 70 kDa |
Product Usage Information
WB | Rat | 1: 800-1: 1500 | ovary, liver |
Background
Golgi serine/threonine protein kinase that phosphorylates secretory pathway proteins within Ser-x-Glu/pSer motifs and plays a key role in biomineralization of bones and teeth . Constitutes the main protein kinase for extracellular proteins, generating the majority of the extracellular phosphoproteome (By similarity). Mainly phosphorylates proteins within the Ser-x-Glu/pSer motif, but also displays a broader substrate specificity (By similarity). Phosphorylates casein as well as a number of proteins involved in biomineralization such as AMELX, AMTN, ENAM and SPP1 . In addition to its role in biomineralization, also plays a role in lipid homeostasis, wound healing and cell migration and adhesion (By similarity).
Images
| Western blot analysis of FAM20C (GB115127) at dilution of 1: 800 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
