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Anti-FAM78B Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Protein FAM78B |
Synonyms: | Protein FAM78B, FAM78B |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse FAM78B |
Uniprot ID: | Q8BQN5 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm |
Product Usage Information
IHC/IF | Human, Mouse, Rat | 1: 500-1: 1500 | breast cancer, esophageal cancer, testis, lung |
Background
Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis.
Images
 | Immunohistochemistry analysis of paraffin embedded human breast cancer using KIAA0907 (GB115337) at dilution of 1: 1000 |
 | Immunohistochemistry analysis of paraffin embedded human esophageal cancer using FAM78B (GB115337) at dilution of 1: 1000 |
 | Immunohistochemistry analysis of paraffin embedded mouse testis using FAM78B (GB115337) at dilution of 1: 1000 |
 | Immunohistochemistry analysis of paraffin embedded rat lung using FAM78B (GB115337) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
