Your shopping cart is empty!
Anti-FBXL3 Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | F-box/LRR-repeat protein 3 |
Synonyms: | FBL3, FBL3A, FBXL3A |
Immunogen: | Recombinant protein corresponding to Mouse FBXL3 |
Uniprot ID: | Q8C4V4 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 49 kDa / 49 kDa |
Product Usage Information
WB | Human, Mouse, Rat | 1: 300-1: 500 | brain |
Background
Substrate-recognition component of the SCF(FBXL3) E3 ubiquitin ligase complex involved in circadian rhythm function. Plays a key role in the maintenance of both the speed and the robustness of the circadian clock oscillation. The SCF(FBXL3) complex mainly acts in the nucleus and mediates ubiquitination and subsequent degradation of CRY1 and CRY2. Activity of the SCF(FBXL3) complex is counteracted by the SCF(FBXL21) complex.
Images
| Western blot analysis of FBXL3 (GB114237) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
