Reactivity: | M,R |
Applications: | IHC |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | FGF10 rabbit polyclonal |
Gene Name: | Fibroblast growth factor 10 |
Synonyms: | Keratinocyte growth factor 2, FGF-10, Fgf10, KGF 2, Produced by fibroblasts of urinary bladder lamina propria |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse FGF10 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Mouse, Rat | 1: 4000-1: 8000 | colon, small intestine, colonitis |
Background
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity of FGF7. Studies of the mouse homolog of suggested that this gene is required for embryonic epidermal morphogenesis including brain development, lung morphogenesis, and initiation of lim bud formation. This gene is also implicated to be a primary factor in the process of wound healing.
Images
Immunohistochemistry analysis of paraffin-embedded mouse colon using FGF10 (GB113167) at dilution of 1: 8000 | |
Immunohistochemistry analysis of paraffin-embedded rat colon using FGF10 (GB113167) at dilution of 1: 8000 | |
Immunohistochemistry analysis of paraffin-embedded mouse small intestine with LPS treated for 24h using FGF10 (GB113167) at dilution of 1: 8000 | |
Immunohistochemistry analysis of paraffin-embedded rat colonitis using FGF10 (GB113167) at dilution of 1: 8000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |