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Anti-FIP200 Rabbit pAb (100 μl)
| Reactivity: | H |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | FIP200 rabbit polyclonal antibody |
Gene Name: | RB1-inducible coiled-coil protein 1 |
Synonyms: | Rb1cc1, RB1CC1, ATG17, CC1, FIP200, PPP1R131, RB1 inducible coiled-coil 1 |
Immunogen: | Recombinant protein corresponding to Mouse FIP200 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 183 kDa |
Observed MW. | 183 kDa |
Uniprot ID: | Q8TDY2 |
Product Usage Information
| Applications | Species | Dilution | Positive Tissue |
| WB | Human | 1: 500-1: 1000 | Hela, MCF7, A20 |
Background
Implicated in the regulation of RB1 expression. Functions as a DNA-binding transcription factor. Is a potent regulator of the RB1 pathway and a mediator that plays a crucial role in muscular differentiation. Expression is, thus, a prerequisite for myogenic differentiation. Involved in autophagy. Required for autophagosome formation. Inhibits PTK2/FAK1 and PTK2B/PYK2 activity and activation of downstream signaling pathways.
Images
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Western blot analysis of FIP 200 (GB11774) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
