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Anti-FKBP2 Rabbit pAb (100 μl)
| Reactivity: | H,M,R & H |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | FK506 binding protein 2, 13kDa |
Synonyms: | 13 kDa FK506 binding protein, 13 kDa FKBP, FK506 binding protein 2, FK506 binding protein 2, 13kDa, FKBP 13, FKBP 2, FKBP13, FKBP2, Immunophilin FKBP13, PPIase, PPIase FKBP2, Rotamase |
Immunogen: | Recombinant protein corresponding to Mouse FKBP2 |
Uniprot ID: | P45878 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 15 kDa / 14 kDa |
Product Usage Information
WB | Human, Mouse, Rat | 1: 300- 1: 600 | brain, liver, placenta |
IHC/IF | Human | 1: 700-1: 1400 | tonsil |
Background
FKBP2 is also named as FKBP13 and belongs to the FKBP-type PPIase family. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. FKBP2 has a 21-amino acid signal peptide and appears to be membrane-associated(PMID:1713687). It is localized to the lumen of the endoplasmic reticulum (ER). FKBP12 and FKBP13 are highly similar proteins, of molecular masses 12 kDa and 13 kDa respectively, with approx.43 % amino acid identity. The strong homology between FKBP12 and FKBP13 suggests that they may share similar biological functions, although, apart from rotamase activity, details relating to the function of either protein are scant(PMID:8373365).
Images
| Western blot analysis of FKBP2 (GB114174) at dilution of 1: 600 |
| Immunohistochemistry analysis of paraffin embedded human tonsil using FKBP2 (GB114174) at dilution of 1: 700 |
| Immunofluorescence analysis of paraffin embedded human tonsil using FKBP2 (GB114174) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
