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Anti-FOXO3A Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | FOXO3A rabbit polyclonal antibody |
Gene Name: | Forkhead box protein O3 |
Synonyms: | FOXO3, AF6q21, FKHRL1, FKHRL1P2, FOXO2, FOXO3A, forkhead box O3 |
Immunogen: | Recombinant protein corresponding to Mouse FOXO3A |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 71 kDa |
Observed MW. | 97 kDa |
Uniprot ID: | Q9WVH4, O43524 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | liver cancer, glioma, lung, brain |
Background
Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'. Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5, promotes induction of miR-34b and miR-34c expression, 2 post-transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent its translation.
Images
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Western blot analysis of FOXO3A (GB11092-1) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
