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Anti-FOXP3 Rabbit pAb (100 μl)
| Reactivity: | H,R,M |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | FOXP3 rabbit polyclonal antibody |
Gene Name: | Forkhead box protein P3 |
Synonyms: | FOXP3, AIID, DIETER, IPEX, JM2, PIDX, XPID, forkhead box P3 |
Immunogen: | Recombinant protein corresponding to Mouse FOXP3 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 47 kDa |
Observed MW. | 47 kDa |
Uniprot ID: | Q99JB6, Q9BZS1 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | inflammatory spleen, thymus gland |
Background
FOXP3 (forkhead box P3), also known as scurfin, is a protein involved in immune system responses. A member of the FOX protein family, FOXP3 appears to function as a master regulator of the regulatory pathway in the development and function of regulatory T cells.Regulatory T cells generally turn the immune response down. In cancer, an excess of regulatory T cell activity can prevent the immune system from destroying cancer cells. In autoimmune disease, a deficiency of regulatory T cell activity can allow other autoimmune cells to attack the body's own tissues.
Images
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Western blot analysis of FOXP3 (GB11093-1) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
