Reactivity: | H,M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | FRMD6/Willin rabbit polyclonal |
Gene Name: | FERM domain-containing protein 6 |
Synonyms: | EX1, FERM domain containing 6, FRMD6, Willin |
Immunogen: | Recombinant protein corresponding to Mouse FRMD6/Willin |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 72 kDa |
Observed MW. | 72 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | spleen, lung |
Background
Willin, also known as FRMD6 or human Expanded (hEx), is a member of the FERM-domain family of cytoskeletal crosslinkers. It is a potent inhibitor of cell proliferation, transformation and modulator of drug sensitivity, suggesting it possesses tumor suppressor properties. Willin is widely expressed in normal tissues. Although willin is found in the cytoplasm and membrane, it localizes to the nuclei of almost all tumors.This antibody was raised against the C-terminal region of human FRMD6 protein and is expected to recognize the endogenous FRMD6.
Images
Western blot analysis of FRMD6 (GB113157) at dilution of 1: 1000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |