Your shopping cart is empty!
Anti-Fas Ligand Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Fas Ligand rabbit polyclonal antibody |
Gene Name: | Tumor necrosis factor receptor superfamily member 6 |
Synonyms: | ALPS1A, APO 1, Apo 1 antigen, APT1, CD95, FAS, FAS1, FASLG receptor, FASTM, TNFRSF6 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse FASL |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Membrane |
Uniprot ID: | P48023, P41047, P36940 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human, Mouse, Rat | 1: 500-1: 3000 | epityphlon, spleen, thymus |
Background
Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both.
Images
|
|
Immunohistochemistry of paraffin embedded human epityphlon using FasL (GB11090-1) at dilution of 1:1500 (400x lens) |
 |
Immunohistochemistry of paraffin embedded mouse spleen using FasL (GB11090-1) at dilution of 1:1500 (400x lens) |
 |
Immunohistochemistry of paraffin embedded rat spleen using FasL (GB11090-1) at dilution of 1:1500 (400x lens) |
 |
Immunofluorescence of paraffin embedded rat spleen using FasL (GB11090-1) at dilution of 1:1500 (400x lens) |
 |
Immunofluorescence of paraffin embedded rat thymus using FasL (GB11090-1) at dilution of 1:1500 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
