Your shopping cart is empty!
| Reactivity: | H |
| Applications: | IHC/IF |
| Host Species: | Mouse |
| Clonality: | Monoclonal |
| Gene Name: | Fascin (55 kDa actin-bundling protein) (Singed-like protein) (p55) |
Gene ID: | 6624 |
Immunogen: | Synthesized peptide derived from human Fascin |
Uniprot ID: | Q16658 |
Source: | Mouse/IgG1, Kappa |
Concentration: | 1 mg/ml |
Purity: | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
Product Usage Information
IHC/IF | Human | 1: 200-1: 500 | classical Hodgkin's lymphoma |
Background
fascin actin-bundling protein 1(FSCN1) Homo sapiens This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15. [provided by RefSeq, Sep 2011],
Images
|
Immunohistochemistry analysis of paraffin embedded human classical Hodgkin's lymphoma using Fascin (GB14083) at dilution of 1: 200 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
