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Anti-FbxL12 Rabbit pAb (100 μl)
| Reactivity: | H |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | F-box/LRR-repeat protein 12 |
Synonyms: | Fbl12, FLJ20188, F-box protein FBL12 |
Immunogen: | Recombinant protein corresponding to Mouse FbxL12 |
Uniprot ID: | Q9EPX5 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 37 kDa / 37 kDa |
Product Usage Information
WB | Human | 1: 1000-1: 2000 | HepG2, Jurkat, K562 |
Background
Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Mediates the polyubiquitination and proteasomal degradation of CAMK1 leading to disruption of cyclin D1/CDK4 complex assembly which results in G1 cell cycle arrest in lung epithelia (By similarity).
Images
| Western blot analysis of FBXL12 (GB115419) at dilution of 1: 2000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
