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| Reactivity: | H |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | GCP4 rabbit polyclonal antibody |
Gene Name: | Gamma-tubulin complex component 4 |
Synonyms: | GCP-4, hGCP4, Gamma-ring complex protein 76 kDa, h76p, hGrip76, TUBGCP4, 76P, GCP4 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse GCP4 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 76 kDa |
Observed MW. | 76 kDa |
Uniprot ID: | Q9UGJ1 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human | 1: 500-1: 800 | MCF-7, HepG2, HCT116 |
Background
This gene encodes a component of the gamma-tubulin ring complex, which is required for microtubule nucleation. In mammalian cells, the protein localizes to centrosomes in association with gamma-tubulin. Crystal structure analysis revealed a structure composed of five helical bundles arranged around conserved hydrophobic cores. An exposed surface area located in the C-terminal domain is essential and sufficient for direct binding to gamma-tubulin. Mutations in this gene that alter microtubule organization are associated with microcephaly and chorioretinopathy.
Images
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Western blot analysis of TUBGCP4 (GB111447) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
