Reactivity: | H |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | Ganglioside-induced differentiation-associated protein 1-like 1 |
Synonyms: | GDAP1L1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse GDAP1-L1 |
Uniprot ID: | Q8VE33 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 42 kDa / 44 kDa |
Product Usage Information
WB | Human | 1: 1000-1: 2000 | HeLa |
Background
The ganglioside GD3 synthase causes cell differentiation with neurite sprouting when transfected into the mouse neuroblastoma cell line Neuro2a. After differentiation, the expression of several genes is upregulated, including one that encodes a protein termed ganglioside-induced differentiation-associated protein 1 (Gdap1). A similar gene was found in humans, and mutations in the human gene are associated with Charcot-Marie-Tooth type 4A disease. The protein encoded by this gene is similar in sequence to the human GDAP1 protein. Several transcript variants encoding different isoforms, as well as a noncoding transcript variant, have been found for this gene.
Images
Western blot analysis of GDAP1L1 (GB115395) at dilution of 1: 1000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |