Reactivity: | M,R & M,R |
Applications: | WB & IHC |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | GGT1/GGT rabbit polyclonal |
Gene Name: | Glutathione hydrolase 1 proenzyme |
Synonyms: | Gamma-glutamyltransferase 1, Gamma-glutamyltranspeptidase 1, GGT 1, Leukotriene-C4 hydrolase, CD224, Ggt, Ggtp, Ggt1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse GGT1/GGT |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Predicted MW. | 62 kDa |
Observed MW. | 55 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 1000-1: 3000 | kidney |
IHC | Mouse, Rat | 1: 2000-1: 4000 | kidney, pancreas |
Background
The enzyme encoded by this gene is a type I gamma-glutamyltransferase that catalyzes the transfer of the glutamyl moiety of glutathione to a variety of amino acids and dipeptide acceptors. The enzyme is composed of a heavy chain and a light chain, which are derived from a single precursor protein. It is expressed in tissues involved in absorption and secretion and may contribute to the etiology of diabetes and other metabolic disorders. Multiple alternatively spliced variants have been identified.
Images
Western blot analysis of GGT1 (GB113421) at dilution of 1: 3000 | |
Immunohistochemistry analysis of paraffin-embedded mouse kidney using GGT1 (GB113421) at dilution of 1: 4000 | |
Immunohistochemistry analysis of paraffin-embedded rat kidney using GGT1 (GB113421) at dilution of 1: 4000 | |
Immunohistochemistry analysis of paraffin-embedded mouse pancreas using GGT1 (GB113421) at dilution of 1: 4000 | |
Immunohistochemistry analysis of paraffin-embedded rat pancreas using GGT1 (GB113421) at dilution of 1: 4000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |