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Anti-Ghrelin Receptor/GHS-R Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Ghrelin Receptor/GHS-R rabbit polyclonal antibody |
Gene Name: | Growth hormone secretagogue receptor type 1 |
Synonyms: | GHS-R, GH-releasing peptide receptor, GHRP, Ghrelin receptor, Ghsr |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Ghrelin Receptor/GHS-R |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 41 kDa |
Observed MW. | 50 kDa |
Uniprot ID: | Q99P50, O08725 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 300-1: 800 | heart |
Background
This gene encodes a member of the G-protein coupledreceptor family. The encoded protein may play a role in energyhomeostasis and regulation of body weight. Two identifiedtranscript variants are expressed in several tissues and areevolutionary conserved in fish and swine. One transcript, 1a,excises an intron and encodes the functional protein; this proteinis the receptor for the Ghrelin ligand and defines a neuroendocrinepathway for growth hormone release. The second transcript (1b)retains the intron and does not function as a receptor for Ghrelin;however, it may function to attenuate activity of isoform 1a.Mutations in this gene are associated with autosomal idiopathicshort stature.
Images
 | Western blot analysis of GHSR (GB112490) at dilution of 1: 300 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
