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| Reactivity: | M,R |
| Applications: | IHC |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Glucagon-like peptide 1 |
Synonyms: | GCG, GLP1, GLP2, GRPP, glucagon, Glucagon, GLP-1, GLP, GLP-2, GRPP Oxyntomodulin, OXM, Proglucagon, OXY |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse GLP1 |
Uniprot ID: | P55095 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Secreted |
Applications
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human, Mouse, Rat | 1:500-1:2000 | pancreas, stomach |
Background
GLP-1 is a potent stimulator of glucose-dependent insulin release. Play important roles on gastric motility and the suppression of plasma glucagon levels. May be involved in the suppression of satiety and stimulation of glucose disposal in peripheral tissues, independent of the actions of insulin. Have growth-promoting activities on intestinal epithelium. May also regulate the hypothalamic pituitary axis (HPA) via effects on LH, TSH, CRH, oxytocin, and vasopressin secretion.
Images
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Immunohistochemistry of paraffin embedded mouse pancreas using GLP1 (GB11335) at dilution of 1:800 (400x lens) |
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Immunohistochemistry of paraffin embedded rat pancreas using GLP1 (GB11335) at dilution of 1:800 (400x lens) |
| Immunofluorescence of paraffin embedded human stomach using GLP1 (GB11335) at dilution of 1:500 (400x lens) |
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Immunofluorescence of paraffin embedded rat pancreas using GLP1 (GB11335) at dilution of 1:500 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
