Your shopping cart is empty!
Anti-GPCR GPR17 Rabbit pAb (100 μl)
| Reactivity: | H,M |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | GPCR GPR17 rabbit polyclonal antibody |
Gene Name: | Uracil nucleotide/cysteinyl leukotriene receptor |
Synonyms: | UDP/CysLT receptor, G-protein coupled receptor 17, Gpr17, R12, Probable P2Y purinoceptor GPR17 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse GPCR GPR17 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 38 kDa |
Observed MW. | 50 kDa |
Uniprot ID: | Q13304, Q6NS65 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse | 1: 300-1: 800 | SH-SY5Y, 293T, N2A |
Background
G protein-coupled receptor 17, GPR17, also known as uracil nucleotide/cysteinyl leukotriene receptor or P2Y-like receptor (P2YL), is a 367 amino acid member of the G-protein coupled receptor 1 family of proteins. While GPR17 is expressed in kidney, heart and umbilical vein endothelial cells, it is expressed in the highest levels in the brain. Upon brain injury, the extracellular concentrations of nucleotides and cysteinyl leukotrienes (CysLTs), two families of endogenous signaling molecules, increase significantly at the site of damage. In some neurons, GPR17, a membrane receptor for uracil nucleotide and CysLTs, is upregulated as well, infiltrating the lesioned area.
Images
 | Western blot analysis of GPR17 (GB112494) at dilution of 1: 300 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
