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Anti-GPNMB Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | GPNMB rabbit polyclonal antibody |
Gene Name: | Transmembrane glycoprotein NMB |
Synonyms: | DC-HIL, Dendritic cell-associated transmembrane protein, Osteoactivin, Gpnmb, Dchil, Hgfin, Nmb |
Immunogen: | Recombinant protein corresponding to Mouse GPNMB |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 64 kDa |
Observed MW. | 64 kDa |
Uniprot ID: | Q14956, Q99P91, Q6P7C7 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | brain, liver, heart |
Background
GPNMB also known as HGFIN, osteoactivin, and DC-HIL, is a type I membrane glycoprotein involved in various biological processes, including inflammation, invasion and metastasis of malignant tumors, cell differentiation, and tissue regeneration. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB acts as an osteogenic factor that stimulates osteoblast differentiation in vivo and in vitro.
Images
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Western blot analysis of GPNMB (GB111475) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
