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Anti-GRP78 BiP Mouse mAb (100 μl)
| Reactivity: | H,M,R & H,M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Mouse |
| Clonality: | Monoclonal |
| Gene Name: | Endoplasmic reticulum chaperone BiP |
Synonyms: | HSPA5, BIP, GRP78, HEL-S-89n, MIF2, Binding immunoglobulin protein, heat shock protein family A (Hsp70) member 5 |
Immunogen: | Recombinant protein corresponding to Mouse GRP78 BiP |
Uniprot ID: | P20029 |
Isotype: | IgG2a,κ |
Purity: | Affinity purification |
Subcellular location: | Endoplasmic reticulum lumen, Melanosome, Cytoplasm |
Predicted MW. / Observed MW. | 78 kDa / 78 kDa |
Product Usage Information
WB | Human, Mouse, Rat | 1: 500-1: 1000 | lung, kidney, colon |
IHC/IF | Human, Mouse, Rat | 1: 1000-1: 2000 | brain, liver cancer |
Background
Probably plays a role in facilitating the assembly of multimeric protein complexes inside the endoplasmic reticulum. Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC10, probably to facilitate the release of DNAJC10 from its substrate.
Images
| Western blot analysis of BiP (GB12098) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin-embedded human liver cancer using BiP (GB12098) at dilution of 1: 2000 |
| Immunohistochemistry analysis of paraffin-embedded mouse brain using BiP (GB12098) at dilution of 1: 2000 |
| Immunohistochemistry analysis of paraffin-embedded rat kidney using BiP (GB12098) at dilution of 1: 2000 |
| Immunofluorescent analysis of paraformaldehyde-fixed human breast cancer using BiP (GB12098) at dilution of 1: 2000 |
| Immunofluorescent analysis of paraformaldehyde-fixed human liver cancer using BiP (GB12098) at dilution of 1: 2000 |
| Immunofluorescent analysis of paraformaldehyde-fixed mouse brain using BiP (GB12098) at dilution of 1: 2000 |
| Immunofluorescent analysis of paraformaldehyde-fixed rat brain using BiP (GB12098) at dilution of 1: 2000 |
| Immunofluorescent analysis of paraformaldehyde-fixed mouse kidney using BiP (GB12098) at dilution of 1: 2000 |
| Immunofluorescent analysis of paraformaldehyde-fixed rat kidney using BiP (GB12098) at dilution of 1: 2000 |
 | Immunofluorescent analysis of paraformaldehyde-fixed rat colon using BiP (GB12098) at dilution of 1: 2000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
