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Anti-Galectin 1 Rabbit pAb (100 μl)
| Reactivity: | M & M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Galectin-1 |
Synonyms: | Gal-1, 14 kDa lectin, Beta-galactoside-binding lectin L-14-I, Galaptin, Lactose-binding lectin 1, Lectin galactoside-binding soluble 1, S-Lac lectin 1, Lgals1, Gbp |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Galectin 1 |
Uniprot ID: | P16045 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Secreted |
Predicted MW. / Observed MW. | 15 kDa / 15 kDa |
Product Usage Information
WB | Mouse | 1: 500-1: 800 | heart, spleen, kidney |
IHC/IF | Mouse, Rat | 1: 500-1: 2000 | brain, heart |
Background
Galectins are a family of animal lectins defined by shared characteristic amino-acid sequences and affinity for β-galactose-containing oligosac-charides . Galectin-1 contains one carbohydrate recognition domain (CRD) and occurs as a monomer as well as a non-covalent homodimer . It is differently expressed by various normal and pathological tissues. Galectin-1 is a multifunctional protein that is involved in cell adhesion, migration, proliferation, apoptosis, inflammation, tumour transformation and growth.Galectin-1 has immunosuppressive and anti-inflammatory properties and has been shown to suppress acute and chronic inflammation and autoimmunity.
Images
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Western blot analysis of Galectin 1 (GB111038) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin-embedded mouse brain using Galectin 1 (GB111038) at dilution of 1: 200 |
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Immunohistochemistry analysis of paraffin-embedded mouse heart using Galectin 1 (GB111038) at dilution of 1: 200 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
