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Anti-Galectin 3 Mouse mAb (100 μl)
| Reactivity: | H |
| Applications: | IHC/IF |
| Host Species: | Mouse |
| Clonality: | Monoclonal |
| Gene Name: | Galectin-3 |
Synonyms: | LGALS3, CBP35, GAL3, GALBP, GALIG, L31, LGALS2, MAC2, lectin, galactoside binding soluble 3, galectin 3 |
Immunogen: | Recombinant protein corresponding to Mouse Galectin 3 |
Uniprot ID: | P16110 |
Isotype: | IgG2a,κ |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm,Secreted,Nucleus |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human | 1: 500-1: 2000 | amygdalitis, colon, colon cancer |
Background
Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity). In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.
Images
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Immunohistochemistry of paraffin embedded human amygdalitis using MAC-2 (GB12246) at dilution of 1: 1000 (400x lens) |
 | Immunohistochemistry of paraffin embedded human colon cancer using MAC-2 (GB12246) at dilution of 1: 1000 (400x lens) |
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Immunohistochemistry of paraffin embedded human colon using MAC-2 (GB12246) at dilution of 1: 1000 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |