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Anti-Galectin 3 Mouse mAb (100 μl)
| Reactivity: | H,R & H,M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Mouse |
| Clonality: | Monoclonal |
| Gene Name: | Galectin-3 |
Synonyms: | LGALS3, CBP35, GAL3, GALBP, GALIG, L31, LGALS2, MAC2, lectin, galactoside binding soluble 3, galectin 3 |
Immunogen: | Recombinant protein corresponding to Mouse Galectin 3 |
Uniprot ID: | P16110 |
Isotype: | IgG1,κ |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm,Secreted,Nucleus |
Predicted MW. / Observed MW. | 26 kDa / 30 kDa |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Rat | 1: 500-1: 1000 | colon |
IHC/IF | Human, Mouse, Rat | 1: 2000-1: 4000 | enteritis, hepatitis, lung, |
Background
Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity). In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.
Images
| Western blot analysis of Galectin-3 (GB12940) at dilution of 1: 1000 |
| Immunohistochemistry of paraffin embedded human lung using Galectin-3 (GB12940) at dilution of 1: 2000 (400x lens) |
| Immunohistochemistry of paraffin embedded mouse hepatitis using Galectin-3 (GB12940) at dilution of 1: 2000 (400x lens) |
| Immunohistochemistry of paraffin embedded mouse pneumonia using Galectin-3 (GB12940) at dilution of 1: 2000 (400x lens) |
| Immunohistochemistry of paraffin embedded rat enteritis using Galectin-3 (GB12940) at dilution of 1: 2000 (400x lens) |
| Immunohistochemistry of paraffin embedded rat pneumonia using Galectin-3 (GB12940) at dilution of 1: 2000 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
