Reactivity: | H,M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | Galectin 3 rabbit polyclonal antibody |
Gene Name: | Galectin-3 |
Synonyms: | LGALS3, CBP35, GAL3, GALBP, GALIG, L31, LGALS2, MAC2, lectin, Galactoside binding soluble 3, Galectin 3 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Human Galectin 3 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 26 kDa |
Observed MW. | 30 kDa |
Uniprot ID: | P17931, P08699, P16110 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 1000-1: 1500 | lung, colon |
Background
Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity). In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.
Images
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Western blot analysis of Galectin-3 (GB11940) at dilution of 1: 1000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |