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Anti-Glucagon Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Glucagon rabbit polyclonal |
Gene Name: | Pro-glucagon |
Synonyms: | GRPP, GCG, GLP 2, GLP1, GLP2, glucagon, GRPP, GRPP Oxyntomodulin, OXM, Proglucagon, OXY |
Immunogen: | Recombinant protein corresponding to Human Glucagon |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Uniprot ID: | P01275, P55095, P06883 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Human, Mouse, Rat | 1: 500-1: 1000 | pancreas |
IF | Human, Mouse, Rat | 1: 500-1: 1000 | pancreas |
Background
Glucagon is a 29-amino acid peptide hormone secreted from the pancreatic alpha cells with a powerful stimulatory effect on hepatic glucose production acting to increase plasma glucose levels. Glucagon is best known as the counter-regulatory hormone to insulin, and normal glucose homeostasis depends largely on the balanced secretion of insulin and glucagon from the pancreatic beta and alpha cells, respectively.The regulation of glucose metabolism by glucagon is mediated by its direct action on the peripheral tissues such as the liver and also by the brain. Glucagon is also released postprandially in a transient manner, which was shown to be involved in inhibition of food intake via reduction of meal size
Images
| Immunohistochemistry analysis of paraffin-embedded human pancreas using Glucagon (GB113496) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin-embedded mouse pancreas using Glucagon (GB113496) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin-embedded rat pancreas using Glucagon (GB113496) at dilution of 1: 1000 |
| Immunofluorescent analysis of paraformaldehyde-fixed human pancreas using Glucagon (GB113496) at dilution of 1: 1000 |
| Immunofluorescent analysis of paraformaldehyde-fixed mouse pancreas using Glucagon (GB113496) at dilution of 1: 1000 |
| Immunofluorescent analysis of paraformaldehyde-fixed rat pancreas using Glucagon (GB113496) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
