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Anti-HIF Prolyl Hydroxylases Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Ph4 rabbit polyclonal antibody |
Gene Name: | Transmembrane prolyl 4-hydroxylase |
Synonyms: | P4H-TM, Hypoxia-inducible factor prolyl Hydroxylase 4, HIF-PH4, HIF-prolyl Hydroxylase 4, HPH-4, P4htm, Ph4 |
Immunogen: | Recombinant protein corresponding to Mouse Ph4 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm |
Uniprot ID: | Q9NXG6, Q8BG58 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human, Mouse, Rat | 1: 400-1: 1300 | brain, colon, colon cancer, liver cancer, lung |
Background
The product of this gene belongs to the family of prolyl 4-hydroxylases. This protein is a prolyl hydroxylase that may be involved in the degradation of hypoxia-inducible transcription factors under normoxia. It plays a role in adaptation to hypoxia and may be related to cellular oxygen sensing.
Images
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Immunohistochemistry of paraffin embedded human colon cancer using P4H (GB111270) at dilution of 1:700 (400x lens) |
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Immunohistochemistry of paraffin embedded human liver cancer using P4H (GB111270) at dilution of 1:700 (400x lens) |
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Immunohistochemistry of paraffin embedded mouse brain using P4H (GB111270) at dilution of 1:700 (400x lens) |
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Immunohistochemistry of paraffin embedded mouse lung using P4H (GB111270) at dilution of 1:700 (400x lens) |
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Immunohistochemistry of paraffin embedded rat brain using P4H (GB111270) at dilution of 1:700 (400x lens) |
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Immunohistochemistry of paraffin embedded rat lung using P4H (GB111270) at dilution of 1:700 (400x lens) |
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Immunofluorescence of paraffin embedded human colon using P4H (GB111270) at dilution of 1:700 (400x lens) |
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Immunofluorescence of paraffin embedded mouse brain using P4H (GB111270) at dilution of 1:700 (400x lens) |
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Immunofluorescence of paraffin embedded mouse lung using P4H (GB111270) at dilution of 1:700 (400x lens) |
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Immunofluorescence of paraffin embedded rat brain using P4H (GB111270) at dilution of 1:700 (400x lens) |
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Immunofluorescence of paraffin embedded rat lung using P4H (GB111270) at dilution of 1:700 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
