Reactivity: | H,M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | Huntingtin-interacting protein 1-related protein |
Synonyms: | HIP 12, HIP1 related protein, HIP12, HIP1R, HIP3, ILWEQ, KIAA0655 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse HIP1R |
Uniprot ID: | Q9JKY5 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 119 kDa / 115 kDa |
Product Usage Information
WB | Human, Mouse, Rat | 1: 2000-1: 4000 | placenta, liver, heart, brain |
Background
Component of clathrin-coated pits and vesicles, that may link the endocytic machinery to the actin cytoskeleton. Binds 3-phosphoinositides (via ENTH domain). May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis.
Images
Western blot analysis of HIP1R (GB114275) at dilution of 1: 2000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |