Reactivity: | R |
Applications: | IHC |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | HIPPI/IFT57 rabbit polyclonal |
Gene Name: | Intraflagellar transport protein 57 homolog |
Synonyms: | DERP8, ESRRBL1, HIP1-interacting protein, HIPPI, IFT57, MHS4R2, Dermal papilla derived protein 8, Huntingtin interacting protein 1 protein interactor, MHS4R2, Vestrogen related receptor beta like 1 |
Immunogen: | Recombinant protein corresponding to Mouse HIPPI/IFT57 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm, Cytoskeleton, Golgi apparatus, Cell projection |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Rat | 1: 2000-1: 4000 | colon |
Background
IFT57, also named as DERP8, ESRRBL1, HIPPI and MHS4R2, belongs to the IFT57 family. It is required for the formation of cilia. IFT57 plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway. It is a component of IFT complex B which composed of IFT88, IFT57, TRAF3IP1, IFT52, IFT27, HSPB11 and IFT20. In contrast to BBS proteins, IFT57 and IFT88 is found in almost every cilium.
Images
Immunohistochemistry analysis of paraffin-embedded rat colon using IFT57 (GB113605) at dilution of 1: 4000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |