Reactivity: | M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | HOXD10 rabbit polyclonal antibody |
Gene Name: | Homeobox protein Hox-D10 |
Synonyms: | Homeobox protein Hox-4.5, Homeobox protein Hox-5.3, Hox-4.5, Hoxd-10, Hoxd10 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse HOXD10 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 38 kDa |
Observed MW. | 38 kDa |
Uniprot ID: | P28359 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Mouse, Rat | 1: 3000-1: 6000 | pancreas |
Background
This gene is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox D genes located on chromosome 2. The encoded nuclear protein functions as a sequence-specific transcription factor that is expressed in the developing limb buds and is involved in differentiation and limb development. Mutations in this gene have been associated with Wilm's tumor and congenital vertical talus (also known as ""rocker-bottom foot"" deformity or congenital convex pes valgus) and/or a foot deformity resembling that seen in Charcot-Marie-Tooth disease.
Images
Western blot analysis of HOXD10 (GB114052) at dilution of 1: 5000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |