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Anti-Haptoglobin Rabbit pAb (100 μl)
| Reactivity: | H |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Haptoglobin |
Synonyms: | BP, HAPT, Haptoglobin, HP, HP2 ALPHA 2, HPA1S, Zonulin |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Haptoglobin |
Uniprot ID: | Q61646 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 39 kDa / 42 kDa |
Product Usage Information
WB | Human | 1: 300-1: 500 | Hep G2 |
Background
As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway (By similarity).
Images
| Western blot analysis of HP (GB115437) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
