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Anti-Hexokinase II Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Hexokinase II rabbit polyclonal antibody |
Gene Name: | Hexokinase-2 |
Synonyms: | HK2, HKII, HXK2, Hexokinase 2, Hexokinase type II,Muscle form hexokinase |
Immunogen: | Recombinant protein corresponding to Mouse Hexokinase II |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 103 kDa |
Observed MW. | 103 kDa |
Uniprot ID: | O08528, P27881 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1:500-1:1000 | heart, muscle |
Background
Hexokinase 2 also known as HK2 is an enzyme which in humans is encoded by the HK2 gene on chromosome 2.In particular, HK2 is ubiquitously expressed in tissues, though it is majorly found in muscle and adipose tissue. In cardiac and skeletal muscle, HK2 can be found bound to both the mitochondrial and sarcoplasmic membrane. The HK2 gene expression is regulated by a phosphatidylinositol 3-kinaselp70 S6 protein kinase-dependent pathway and can be induced by factors such as insulin, hypoxia, cold temperatures, and exercise. Its inducible expression indicates its adaptive role in metabolic responses to changes in the cellular environment.
Images
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Western blot analysis of HK2 (GB11866) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
