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Anti-Histone H1.2 Rabbit pAb (100 μl)
| Reactivity: | H |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Histone H1.2 |
Synonyms: | 1.2, H1F2, HIST1H1C, histone, histone cluster 1, H1c, Histone H1.2, Histone H1d |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Histone H1.2 |
Uniprot ID: | P15864 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus |
Product Usage Information
IHC/IF | Human | 1: 800-1: 2400 | breast cancer, esophageal carcinoma, colon cancer |
Background
Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation (By similarity).
Images
| Immunohistochemistry analysis of paraffin embedded human breast cancer using Histone H1.2 (GB115296) at dilution of 1:800 |
| Immunohistochemistry analysis of paraffin embedded human esophageal carcinoma using Histone H1.2 (GB115296) at dilution of 1:800 |
| Immunohistochemistry analysis of paraffin embedded human colon cancer using Histone H1.2 (GB115296) at dilution of 1:800 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
