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Anti-Hsc70 Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Hsc70 rabbit polyclonal antibody |
Gene Name: | Heat shock cognate 71 kDa protein |
Synonyms: | Heat shock 70 kDa protein 8, Lipopolysaccharide-associated protein 1, LAP-1, LPS-associated protein 1, HSC70, HSP73, HSPA10, HSPA8 |
Immunogen: | Recombinant protein corresponding to Human Hsc70 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 71 kDa |
Observed MW. | 71 kDa |
Uniprot ID: | P11142 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 1000-1: 2000 | brain, stomach |
Background
HSPA8 (also known as HSC70) is a member of the HSPA (HSP70) family of heat-shock proteins which are highly conserved chaperons implicated in protein folding, protein refolding, protein transport, and protein targeting. HSPA8 is a constitutively expressed cytosol/nuclear protein able to translocate between cytoplasm and nucleus. Recently it has been reported that HSPA8 can interact with α-synuclein, the critical pathological protein of Parkinson’s disease, indicating its implication in neurodegenerative disease.
Images
 | Western blot analysis of HSP73 (GB112546) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
