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Anti-Hsp47 Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Hsp47 rabbit polyclonal antibody |
Gene Name: | Serpin H1 |
Synonyms: | 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serine protease inhibitor J6, Serpinh1, Cbp1, Hsp47 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Hsp47 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm |
Uniprot ID: | P50454, P19324 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human, Mouse, Rat | 1: 500-1: 3000 | colon cancer, myeloma, ovarian cancer, placenta, skin |
Background
Hsp47, also known as colligin and gp46, is an ER-resident collagen-specific stress glycoprotein involved in the synthesis and assembly of varoius collagens as a molecular chaperone. Hsp47 is a member of the serpin superfamily, but localizes to the ER via binding of its C-terminal RDEL sequence to KDEL receptors in the ER. Hsp47 binds procollagen co-translationally as it enters the ER, and dissociates prior to its secretion.
Images
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Immunohistochemistry of paraffin embedded human colon cancer using HSP47 (GB111425) at dilution of 1:1600 (400x lens) |
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Immunohistochemistry of paraffin embedded human ovarian cancer using HSP47 (GB111425) at dilution of 1:1600 (400x lens) |
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Immunohistochemistry of paraffin embedded mouse myeloma using HSP47 (GB111425) at dilution of 1:1600 (400x lens) |
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Immunohistochemistry of paraffin embedded mouse skin using HSP47 (GB111425) at dilution of 1:1600 (400x lens) |
| Immunohistochemistry of paraffin embedded rat skin using HSP47 (GB111425) at dilution of 1:1600 (400x lens) |
| Immunofluorescence of paraffin embedded human colon cancer using HSP47 (GB111425) at dilution of 1:800 (400x lens) |
| Immunofluorescence of paraffin embedded mouse placenta using HSP47 (GB111425) at dilution of 1:800 (400x lens) |
| Immunofluorescence of paraffin embedded mouse skin using HSP47 (GB111425) at dilution of 1:800 (400x lens) |
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Immunofluorescence of paraffin embedded rat placenta using HSP47 (GB111425) at dilution of 1:800 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
