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Anti-IFT88 Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | IFT88 rabbit polyclonal |
Gene Name: | Intraflagellar transport protein 88 homolog |
Synonyms: | IFT88, TPR repeat protein 10, TTC10, Recessive polycystic kidney disease protein Tg737, Tg737, Tg737Rpw, TgN737Rpw |
Immunogen: | Recombinant protein corresponding to Mouse IFT88 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 93 kDa |
Observed MW. | 93 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 1000-1: 2000 | testis |
Background
Intraflagellar transport (IFT), mediated by molecular motors and IFT particles, is an important transport process that occurs in the cilium and has been shown to be essential for the assembly and maintenance of cilia and flagella in many organisms. IFT88 (intraflagellar transport protein 88; also known as TG737 or TTC10) is a component of IFT particles and required for cilium biogenesis. Defects in IFT88/Tg737 lead to polycystic kidney disease . IFT88 localizes to spindle poles during mitosis and is required for spindle orientation in mitosis . This antibody was raised against the C-terminal region of human IFT88 and can detect the endogenous level of IFT88.
Images
 | Western blot analysis of IFT88 (GB113652) at dilution of 1: 2000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
