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Anti-IGF1 Receptor Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | IGF1 Receptor rabbit polyclonal antibody |
Gene Name: | Insulin-like growth factor 1 receptor |
Synonyms: | Insulin-like growth factor I receptor, IGF-I receptor, CD221, JTK13, CD221 antigen, IGFIRC, Insulin like growth factor 1 receptor precursor |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Human IGF1 Receptor |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 155 kDa |
Observed MW. | 95/200 kDa |
Uniprot ID: | P08069, Q60751, P24062 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | C2C12, HEK293, MCF-7, NIH/3T3 |
Background
IGF1R, also named as CD221, is a receptor tyrosine kinase which mediates actions of insulin-like growth factor 1 (IGF1). IGF1R binds IGF1 with high affinity and IGF2 and insulin (INS) with a lower affinity, the activated IGF1R is involved in cell growth and survival control. It is crucial for tumor transformation and survival of malignant cell. IGF1R is a heterotetrameric receptor, composed of two alpha subunits (130 kDa each) and two beta subunits (~98 kDa each) .
Images
 | Western blot analysis of IGF1R (GB112542) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
