Reactivity: | M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | IGFBP1 rabbit polyclonal |
Gene Name: | Insulin-like growth factor-binding protein 1 |
Synonyms: | AFBP, hIGFBP 1, IBP-1, IBP1, IGF binding protein 1, IGFBP25, IGFBP 1, IGFBP1, Placental protein 12, PP12, Binding protein 28, Binding protein 26, Binding protein 25 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse IGFBP1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 30kDa |
Observed MW. | 30kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 300-1: 600 | pancreas |
Background
This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP N-terminal domain and a thyroglobulin type-I domain. The encoded protein, mainly expressed in the liver, circulates in the plasma and binds both insulin-like growth factors (IGFs) I and II, prolonging their half-lives and altering their interaction with cell surface receptors. This protein is important in cell migration and metabolism. Low levels of this protein may be associated with impaired glucose tolerance, vascular disease and hypertension in human patients.
Images
Western blot analysis of IGFBP1 (GB113739) at dilution of 1: 600 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |