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Anti-IL-21R Rabbit pAb (100 μl)
| Reactivity: | H |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | IL-21R rabbit polyclonal antibody |
Gene Name: | Interleukin-21 receptor |
Synonyms: | IL-21R, Novel interleukin receptor, CD360, IL21R, NILR, IL-21 receptor |
Immunogen: | Recombinant protein corresponding to Mouse IL-21R |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane (Cytoplasm) |
Uniprot ID: | Q9HBE5 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human | 1: 1000-1: 4000 | colon, liver cancer, lung cancer |
Background
IL21R, a receptor for interleukin-21 (also termed NILR for novel Interleukin receptor) is a new member of the class I cytokine receptor family. IL-21R forms a complex with the common cytokine receptor -gamma chain, -gammac, and mediates IL-21 signaling. Both IL-21R and the -gammac are necessary for the IL-21 function. IL-21 and its receptor activate JAK-STAT signaling pathway.IL-21 plays a role in the proliferation and maturation of NK, B and T cell populations.
Images
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Immunohistochemistry of paraffin embedded human colon using IL21R (GB111382) at dilution of 1:1700 (400x lens) |
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Immunohistochemistry of paraffin embedded human liver cancer using IL21R (GB111382) at dilution of 1:1700 (400x lens) |
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Immunohistochemistry of paraffin embedded human lung cancer using IL21R (GB111382) at dilution of 1:1700 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
