Your shopping cart is empty!
| Reactivity: | M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | IL-22 rabbit polyclonal antibody |
Gene Name: | Interleukin-22 |
Synonyms: | IL22, IL-21, IL-22, IL-D110, IL-TIF, ILTIF, TIFIL-23, TIFa, zcyto18, interleukin 22 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse IL-22 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Secreted |
Uniprot ID: | Q9JJY9 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human, Mouse, Rat | 1:400-1:800 | lung, tonsil |
Background
IL-22 biological activity is initiated by binding to a cell-surface complex composed of IL-22R1 and IL-10R2receptor chains and further regulated by interactions with a soluble binding protein, IL-22BP, which shares sequence similarity with an extracellular region of IL-22R1 (sIL-22R1). IL-22 and IL-10 receptor chains play a role in cellular targeting and signal transduction to selectively initiate and regulate immune responses.IL-22 can contribute to immune disease through the stimulation of inflammatory responses, S100s and defensins.
Images
|
Immunohistochemistry of paraffin embedded mouse lung using IL-22 (GB11259) at dilution of 1:400 (400x lens) |
| Immunofluorescence of paraffin embedded human tonsil using IL-22 (GB11259) at dilution of 1:400 (400x lens) |
|
Immunofluorescence of paraffin embedded mouse tonsil using IL-22 (GB11259) at dilution of 1:400 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
