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Anti-IL-22RA1 Rabbit pAb (100 μl)
| Reactivity: | M |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | IL-22RA1 rabbit polyclonal |
Gene Name: | Interleukin-22 receptor subunit alpha-1 |
Synonyms: | IL22RA1, CRF2-9, IL22R, IL22R1, interleukin 22 receptor subunit alpha 1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse IL-22RA1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Human, Mouse, Rat | 1:200-1:400 | colon, stomach, lung, kidney, spleen |
IF | Human, Mouse, Rat | 1:200-1:400 | colon, stomach, lung, kidney, spleen |
Background
Component of the receptor for IL20, IL22 and IL24. Component of IL22 receptor formed by IL22RA1 and IL10RB enabling IL22 signaling via JAK/STAT pathways. IL22 also induces activation of MAPK1/MAPK3 and Akt kinases pathways. Component of one of the receptor for IL20 and IL24 formed by IL22RA1 and IL20RB also signaling through STATs activation. Mediates IL24 antiangiogenic activity as well as IL24 inhibitory effect on endothelial cell tube formation and differentiation.
Images
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Immunohistochemistry analysis of paraffin-embedded human colon using IL-22RA1 (GB11302) at dilution of 1: 200 |
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Immunohistochemistry analysis of paraffin-embedded human stomach using IL-22RA1 (GB11302) at dilution of 1: 200 |
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Immunohistochemistry analysis of paraffin-embedded mouse lung using IL-22RA1 (GB11302) at dilution of 1: 200 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
