Reactivity: | H,M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | IL-27-A rabbit polyclonal antibody |
Gene Name: | Interleukin-27 subunit alpha |
Synonyms: | Il27, IL27A, Interleukin 27, Interleukin 27 subunit alpha, Interleukin 30, IL30, IL 27 p28 subunit, IL27p28 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse IL27A |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 27 kDa |
Observed MW. | 28 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | liver, splenitis, pneumonia |
Background
Interleukin 27 (IL-27) is a member of the IL-12 cytokine family. It is a heterodimeric cytokine that is composed of two distinct genes, Epstein-Barr virus-induced gene 3 (EBI3) and IL-27p28. IL-27 is expressed by antigen presenting cells and interacts with a specific cell-surface receptor complex known as IL-27 receptor (IL-27R). This receptor consists of two proteins, IL-27ɑ and gp130. IL-27 induces differentiation of the diverse populations of T cells in the immune system and also upregulates IL-10.
Images
Western blot analysis of IL-27A (GB11661) at dilution of 1: 500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |