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Anti-Integrin linked ILK Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Integrin linked ILK rabbit polyclonal antibody |
Gene Name: | Integrin-linked protein kinase |
Synonyms: | Ilk, 59 kDa serine/threonine-protein kinase, epididymis secretory protein Li 28, ILK-1, P59, kinase-2, integrin-linked kinase, integrin-linked ILK-2, Integrin-linked protein kinase, p59ILK |
Immunogen: | Recombinant protein corresponding to Mouse Integrin linked ILK |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 51 kDa |
Observed MW. | 51 kDa |
Uniprot ID: | Q13418, O55222, Q99J82 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | lung, uterus, heart, liver |
Background
This Integrin-linked kinase (ILK) gene encodes a protein with a kinase-like domain and four ankyrin-like repeats. The encoded protein associates at the cell membrane with the cytoplasmic domain of beta integrins, where it regulates integrin-mediated signal transduction. Activity of this protein is important in the epithelial to mesenchymal transition, and over-expression of this gene is implicated in tumor growth and metastasis. This protein belongs to the protein kinase super family. It can be autophosphorylated on serine residues. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.
Images
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Western blot analysis of ilk (GB11963) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
