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| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Integrator complex subunit 4 |
Synonyms: | INTS4, MST093 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse INTS4 |
Uniprot ID: | Q8CIM8 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 108 kDa / 108 kDa |
Product Usage Information
WB | Human, Mouse, Rat | 1: 2000-1: 3000 | Jurkat, brain |
Background
Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex.
Images
| Western blot analysis of INTS4 (GB115159) at dilution of 1: 2000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
